Interview preparation · Clinical statistical programming

From Endpoint
to TLF

A principal-level narrative playbook. Three therapeutic areas — oncology, CNS and psychiatry — each walked end to end from the protocol objective through SDTM and ADaM to the procedures, the tables, the figures and the read-out.

16
audio tracks, ~72 minutes, the same material spoken
39
page PDF, three studies end to end, code and traps
Download the study pack
216 KB · 39 pages · A4, print-ready
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full-screen reader · best on mobile

The spine

Seven links, always in the same order, whatever the therapeutic area. Learn the spine once and the disease becomes interchangeable detail.

#LinkThe sentence you say
1Objective“The primary objective was to demonstrate …”
2Endpoint + estimand“The primary endpoint was X, and the estimand treated discontinuation as …”
3Collection“That came off the CRF as … , collected at these visits.”
4SDTM“Which lands in domain … , with these variables carrying the signal.”
5ADaM“Which I derived into … , PARAMCD = … , AVAL = … , with these flags.”
6Analysis“The SAP called for … , which is PROC … with these options.”
7Output + read-out“That produced table … and figure … . The result was …”

Read it here

The whole pack, inline. Use the viewer's own search to jump to a topic — every module carries its own traps and rapid-fire drill.

Not rendering? Some mobile browsers refuse to embed PDFs — use Open in a new tab above.

Audiobook

Same material, spoken. Built to be listened to on a walk, daily, until the chain comes without effort. Start with the orientation track.

Orientation

Module 1

Module 2

Module 3

Module 4

Module 5

How to use this. Listen straight through once without trying to retain anything, then return to the module you feel least comfortable in and repeat it three or four times. Read the PDF alongside — the audio carries the reasoning, the traps and the wording; the PDF carries the code and the tables, and you cannot learn a PROC statement by listening.
Two honest caveats. The numbers in the read-outs are illustrative — typical of published results in each area, there so the narrative has a shape to land on. Substitute real figures from studies you actually worked on before quoting them. And no SAS in the pack has been executed; every option is explained and defensible, but these are interview artefacts, not validated programs.